NF-κB also regulates histone deacetylase 3 (HDAC3) expression, and MSC-Exos inhibit p65 phosphorylation, NF-κB transcriptional activity, HDAC3 expression, and neuroinflammation in subarachnoid hemorrhage (Lai et al. 2020). This evidence concerns the gene NFKB1 and subarachnoid hemorrhage.