The study of Orywall et al. on serum ADH (alcohol dehydrogenase) isoenzymes and ALDH (aldehyde dehydrogenase) activity found a significantly higher total activity of ADH in sera of both, low-grade and high-grade BC patients, with ADH activity (AUC—0.848; SN 81.5%; SP 98.1%; PPV 97.4%; NPV 92.3%) (Orywal et al. 2017, 2018). The gene discussed is AVP; the disease is breast cancer.