CD4 and ulcerative colitis: Adaptive immune abnormalities in ulcerative colitis are defined by mucosal CD4+ cells, atypical Th2 responses represented by UC, such as interleukin 13 represented by the presence of secreted atypical natural killer T cells in the colon, intestinal inflammation of the tract is largely dependent on T cell processes, and over the past few decades, the pathogenic mechanisms of T cells have been well defined in research, as well as the characteristics and potential to limit the number of disease-regulating T cells [37, 38].