It was well known that lipo‐metabolism in cancer cells is closely associated with critical lipogenic enzymes, including fatty acid synthase (FASN),7 acetyl‐CoA carboxylase alpha (ACC1),44, 45 SCD1,46, 47 SERPINE1 MRNA binding protein 1 (SERBP1)48 and ATP citrate lyase (ACLY).49 The gene discussed is SCD; the disease is cancer.