HMOX1 and intestinal disorder: We observed that the administration of Res effectively attenuated DSS‐induced IECs barrier dysfunction and the protective effect was associated with anti‐inflammatory, antioxidant, increasing TJ proteins expression and activating the Nrf2/HO‐1 pathway (Figure 6), indicating that Res might be a potent, safe, and economical option for the treatment of intestinal diseases.