The importance of the FAK/PI3K/Akt/mTOR pathway in OSA is accentuated by a genomic study,88 and experimental findings including that CXCL1 promotes OSA lung metastasis via the CXCR2/FAK/PI3K/Akt pathway and that anti‐OSA effects can be achieved by inhibiting the FAK/PI3K/Akt pathway.89, 90. This evidence concerns the gene CXCR2 and obstructive sleep apnea syndrome.