Recent studies have identified Derlin-1 (the protein product of DERL1) as a growth promoter in breast cancer, and patients with a high expression of Derlin-1 were found to have a significantly lower prognosis than patients with a low expression of Derlin-1 (Liu et al. 2020, Zeng et al. 2020). The gene discussed is DERL1; the disease is breast cancer.