ILUSTRO Trial (NCT03505320): A phase II clinical trial was conducted to assess safety and efficacy of zolbetuximab alone (cohort 1, n=30), zolbetuximab in combination with mFOLFOX6 (cohort 2, n=21) or zolbetuximab plus pembrolizumab (cohort 3, n=3) in advanced GC/GEJ adenocarcinoma with moderate (≥50% but <75%) to high (≥75%) CLDN18.2+ staining. The gene discussed is CLDN18; the disease is gastric cancer.