ABCD1 and X-linked adrenoleukodystrophy: Adrenomyeloneuropathy (AMN) and cerebral adrenoleukodystrophy (CALD) are the clinical forms of X-linked adrenoleukodystrophy (X-ALD), an inherited progressive neurometabolic disease caused by mutations in the ABCD1 gene and the accumulation of very long-chain fatty acids in cells and tissues (1).