IL17A and psoriasis: The study ficused at three compounds identified in M. oleifera extracts: niazirin, marmumoside A and D-glucoside-3-O-β-sitosterol. Their effect on the expression of Th17-related cytokines was investigated. i.e., IL-12/IL-23 p40. IL-17A. IL-22 and IL-23 p19 using the THP-1 cell line stimulated with LPS. Data were collected at 0.5 h after 2 h for quantification of gene expression. 12-O-tetradecanoyl phorbol-13-acetate (TPA) was used in the study. to induce skin lesions that mimic those caused by psoriasis in mice