After that, they further showed that the rAAV‐vector‐treated G6pc−/− mice expressing 0.2% of normal hepatic G6Pase‐α activity experienced hypoglycemia, while expressing 0.5%–1.3% of normal hepatic G6Pase‐α activity showed no evidence of HCA formation. This evidence concerns the gene G6PC1 and hepatocellular adenoma.