We found that TREM1 expression was negatively correlated with tumor purity (TCGA-seq: R= -0.7350, P <0.0001; CGGA-seq: R= -0.7126, P <0.0001) in the TCGA and CGGA datasets (Figure 5A and Supplementary Figure 10A). This evidence concerns the gene TREM1 and neoplasm.