The tumor volume within 30 days after inoculation was analyzed, the group of inhibitors and oe-S100A16 could increase the tumor growth of mice, while sh-lnc group notablely repressed the tumor growth, and there was no significant difference in sh-lnc+inhibitors or sh-lnc+oe-S100A16 group (Figure 6A). This evidence concerns the gene S100A16 and neoplasm.