UBE2C and glioblastoma: According to data from the HPA database, UBE2C exhibited high expression levels in BRCA, Carcinoid, CESC, COAD, GBM, HNSC, LIHC, lung cancer, lymphoma, OV, PAAD, PRAD, KIRC, KIRP, KICH, SKCM, STAD, TGCT, and THCA (Figure 8B), and representative immunohistochemical results are displayed in Figure 8C. Subsequently, the subcellular distribution of UBE2C was determined via immunofluorescence localization in MCF-7, PC-3, and U2OS cells, revealing that UBE2C primarily localized to the nucleus, microtubules, and endoplasmic reticulum (ER) (Figure 8D).