What's more, UBE2C expression was positively linked with MLH1, MSH2, MSH6 and PMS2 in most cancers except KIRC and THCA, but was negatively correlated with MLH1 and PMS2 in BRCA, KIRP, TGCT and THYM (Figure 9E, p < 0.05&p < 0.001& p < 0.0001). This evidence concerns the gene MSH2 and cancer.