Mice exhibited a statistically significant reduction in inflammation grade and incidence of tumors, including adenocarcinoma, ranging from 38 to 50% and 38 to 63%, respectively. Treatments resulted in the normalization of colonic GST and NQO1 activities, as well as erythrocyte GSH levels, and a significant reduction in cecal and colonic β‐GA, indicating an improvement in intestinal parameters, inflammatory states, and redox states of the animals. The gene discussed is NQO1; the disease is adenocarcinoma.