Studies have shown that the intracellular segment gene (NICD) of the Notch 1 receptor transfected with adenovirus after myocardial infarction may improve hemodynamics, suggesting that Notch gene re‐expression was an adaptive response secondary to myocardial injury and is closely associated with the repair and regeneration of viable myocardium (Kasahara et al., 2013). Here, NOTCH1 is linked to myocardial infarction.