MYD88 and retinitis pigmentosa 1: Another strategy tested in the rd10 mouse model of RP to restrain activation of the TLR pathway was based on the selective block of the downstream adaptor MyD88, for example by interfering with the interaction of MyD88 death domain with interleukin-1 receptor-associated kinase 2/4 (IRAK2/4), which is necessary for the signaling mediated by TLRs (Chen et al., 2020; Garces et al., 2020).