A systematic review by Thevi et al. advocated using vitamin C for wound healing as it increases recovery rates and leukocyte ascorbic acid levels.57, 58, 59 Emerging evidence of vitamin D deficiency has underscored its potential implication in the wound-healing process.60, 61, 62 A case series by Siregar found that it binds with Vitamin D receptors via calcitriol, regulating the production of several receptors and upregulating the innate immune system while weakening the adaptive immune system.63 Here, VDR is linked to vitamin D deficiency.