EGFR and burning mouth syndrome: On the other hand, for patients with symptomatic BMs, uLT is recommended (radiosurgery or radiation therapy and/or surgery) as LT shows great potential for instant alleviation of neurological symptoms among them, indicating a novel BM management strategy of LT plus EGFR-TKIs (Rhun et al. 2021; Vogelbaum et al. 2022; Yang et al. 2017; Ni et al. 2019; Bhandari et al. 2021; Gondi et al. 2022).