The results showed that ATP6AP1 expression levels were significantly related to most immunosuppressive molecules, including TNFRSF8, CD40, PDCD1, TNFRSF18, TNFRSF25, TNFRSF4, TNFRSF14, VSIR, CD276, VTCN1, and BTLA in CRC (all p < 0.05, Fig. 4F). Here, PDCD1 is linked to colorectal carcinoma.