F10 and atrial fibrillation: Direct oral anticoagulant agents (DOACs), including thrombin inhibitors (dabigatran) and factor Xa (FXa) inhibitors (apixaban, rivaroxaban, and edoxaban), are recommended as the first choice for anticoagulation in patients with venous thromboembolism (VTE)1,2 and nonvalvular atrial fibrillation (AF)3.