ACACB up-regulated in small-bowel strictures of the marmoset,6STEAP1B linked to adult IBD,7DSG1as a serologic marker of complicated CD,8 and CYP4F2 in which the specific polymorphism identified in this study (rs2108622) also has been observed to associate significantly with CD by Costea et al.9 This evidence concerns the gene ACACB and Cowden disease.