TMEM175 and Parkinson disease: For example, Rizig and coworkers identified a GBA1 risk variant in African and African-admixed PD cohorts that is distinct from previously identified GBA1 risk alleles [84], Foo and coworkers found SV2C and WBSCR17 as novel hits, along with GBA1, TMEM175, and LRRK2 etc., in East Asian cohorts [85], an Indian study found hits such as SNCA, TMEM175, GBA1, PRKN and BSN [86], and a multi-ethnic study including Latin and Latin-admixed populations identified SNCA, STXBP6 and RPS6KA2 as novel loci in their meta-analysis [87].