In genetic FTD, mutations were identified in microtubule-associated protein tau (MAPT) [82], progranulin (GRN) [83,84], chromosome 9 open reading frame 72 (C9orf72) [85,86], and more rarely in other genes including charged multivesicular body protein 2B (CHMP2B) [87], FUS [88], and TANK-binding kinase 1 (TBK1) [89,90]. The gene discussed is CHMP2B; the disease is frontotemporal dementia.