Strikingly, ectopic overexpression of miR-590-3p in MM cell lines was able to strongly counteract the increase of TAZ expression at transcriptional and protein levels produced by Che-1 depletion, (Fig. 1I and Supplementary Figs. S4L–M), thus confirming that Che-1 inhibited TAZ expression in MM by inducing EIF4H/miR-590-3p transcription. The gene discussed is AATF; the disease is Miyoshi myopathy.