Interestingly, inhibition of PARG was found to radiosensitise FaDu (Fig. 6O; p < 0.0001) and UMSCC6 cells (Fig. 6P; p = 0.12) to low-LET protons, suggests that PARG inhibition in HNSCC cells may have more of a general radiosensitisation role. The gene discussed is PARG; the disease is head and neck squamous cell carcinoma.