Furthermore, depletion of OGG1, PARG, Pol β, or XRCC1 had no impact on the radiosensitivity of HNSCC cells, specifically UMSCC74A (Supplementary Fig. 2E–H), UMSCC6 (Supplementary Fig. 2I–L) and FaDu (Supplementary Fig. 2M–P), to X-rays. The gene discussed is OGG1; the disease is head and neck squamous cell carcinoma.