GLIPR1 and neoplasm: To determine the efficacy in vivo, C-NKG mice were inoculated subcutaneously with HGC27-Scramble (HGC27-sc) or HGC27-shRNA-GLIPR1 (HGC27-Gsh) tumor cells, followed by intravenous injection of 15B6 or 15B6ss CAR-T cells 7 day later (Fig. 4G).