Remarkably, higher expression of PCDH8 was observed in several cancers, such as bladder urothelial carcinoma, breast invasive carcinoma, colon adenocarcinoma, lung squamous cell carcinoma, pancreatic adenocarcinoma, pheochromocytoma, paraganglioma, THCA, esophageal carcinoma, thymoma, and uterine carcinosarcoma. This evidence concerns the gene PCDH8 and pancreatic adenocarcinoma.