PCDH8 and cancer: The absence of protocadherin (PCDH) proteins, such as PCDH8, impacts the development of various types of human cancers, including colon, liver, renal, prostate, breast, nasopharyngeal, and lung cancer, as well as astrocytoma (Stassar et al. 2001; Chen et al. 2002; Okazaki et al. 2002; Waha et al. 2005; Imoto et al. 2006; Ying et al. 2006; Yu et al. 2008, 2009).