Our results indicate that the expression of PCDH8 is significantly associated with the type of primary neoplasm focus (Table 1, Fig. 2A), the PFI (Fig. 2B), history of thyroid gland disorders (Fig. 2C), methylation levels (Fig. 2D), age (Fig. 2E), race (Fig. 2F), pathologic stage (Fig. 2G), and thyroglobulin levels (Fig. 2H). This evidence concerns the gene PCDH8 and neoplasm.