The cRGD peptide is highly adhesive to the GP IIb/IIIa complex and has emerged as the targeting ligand coupling with IONPs to target platelets at the plaque site in some reported studies.[35] Additionally, the platelet‐specific collagen receptor GPVI, mediating platelet activation, adhesion, and aggregation, has been studied as a promising antiplatelet target for atherosclerosis.[42]. This evidence concerns the gene GP6 and atherosclerosis.