Subsequently, they coupled VCAM‐1 and Cy5.5 to this system via amidation reactions, forming a theranostic nanoplatform with dual‐modal imaging capabilities (MRI and fluorescence imaging) and targeted treatment for atherosclerosis.[75] Furthermore, paclitaxel, a natural anticancer drug known for its antiproliferative and immunomodulatory effects, has shown effectiveness in alleviating atherosclerotic lesions by inhibiting macrophage migration, vascular smooth muscle cell hyperproliferation, and intimal invasion in a rabbit model of atherosclerosis.[100] Thus, Dong et al. This evidence concerns the gene VCAM1 and atherosclerosis.