Moreover, secondary TDP-43 pathology has been found in other disorders including Alzheimer's disease (AD), Lewy body disease (LBD), argyrophilic grain disease (AGD), Parkinsonism or Huntington's disease (Amador-Ortiz et al., 2007; Chanson et al., 2010; Davidson et al., 2009; Josephs et al., 2014; Kabashi et al., 2008; Schwab et al., 2008; Sreedharan et al., 2008). The gene discussed is TARDBP; the disease is Alzheimer disease.