CHEK2 and familial papillary or follicular thyroid carcinoma: Additionally, germline variants in DNA repair related-genes, namely BRCA1/2, ATM, CHEK2, and MSH6 have been recently reported in cases with FNMTC and NMTC (19, 20, 21, 22, 23, 24, 25), suggesting a role for these genes in FNMTC pathogenesis.