CLEC7A and autoimmune disease: The Dectin-1 cluster is a subgroup of CLRs, consisting of seven structurally related receptors including CLEC12A, CLEC-2, CLEC12B, CLEC9A, CLEC-1, Dectin-1, and LOX-1, which are involved in regulation of inflammation, infection, and other autoimmune diseases (2).