IGHE and asthma: Current review articles, including key clinical trials conducted so far, emphasize not only the reduction in exacerbations but also improvements in asthma-related quality of life questionnaires, as well as reduced Forced Expiratory Volume in 1 s, in L (FEV1), Fractional Exhaled Nitric Oxide (FeNO), serum eosinophils, and total serum IgE.119, 120, 121, 122, 123