Among the three new [99mTc]Tc-DB15-base analogues designed to accommodate trivalent radiometals for theranostic use, [111In]In-AU-SAR-M1 turned out to be the most promising, owing to its high GRPR-specific tumor uptake and retention in combination with a low and declining uptake in healthy tissues. The gene discussed is GRPR; the disease is neoplasm.