N4-AMA-DIG-[DPhe6,Sar11,LeuNHEt13]BBN(6–13); N4, 6-carboxy-1,4,8,11-tetraazaundecane)) (Nock et al. 2021, 2018), turned out to be NEP-resistant, showing improved GRPR-mediated tumor uptake and retention in murine models. The gene discussed is GRPR; the disease is neoplasm.