The combination treatment of PTT and silencing Gal-9 with FSGG/siGal-9 plus laser irradiation plus magnet field (“FSGG/siGal-9+Laser+M”) further suppressed tumor growth (Fig. 5c) and decreased the tumor weight (Fig. 5d), compared to the mice receiving single treatment with the photothermal effects (“FSGG/siGL2+Laser+M”) or gene silencing of Gal-9 (“FSGG/siGal-9+M”). This evidence concerns the gene LGALS9 and neoplasm.