Our results firstly discovered that PTT increased anti-tumor immunity on the basis of effectively suppressing Gal-9 in splenic DCs (Fig. 6b), reducing T cell apoptosis (Fig. 6d), inducing IL-2 release in spleen (Fig. 6e), enhancing tumor-Ag-specific T cell response (Fig. 6j). This evidence concerns the gene LGALS9 and neoplasm.