Thirdly, due to the retrospective nature of the study, several potentially residual confounders related to additional pharmacological treatment, relevant chronic conditions such as paroxysmal/persistent atrial fibrillation, mitral regurgitation, history of important events—e.g., stroke—and certain biochemical markers including estimated glomerular filtration rate, creatine phosphokinase, brain natriuretic peptide, troponin, and reperfusion status were unavailable. Here, NPPB is linked to mitral valve insufficiency.