Genes mediating mitochondrial and peroxisomal fission, and pexophagy show no tissue specificity [50] (Figs. 1a and 2e,f), except for the neuronal fission factor GDAP1 [4], and cerebral enrichment of the E3 ubiquitin ligase TRIM37 (Fig. 2e, f), which corresponds to the primary neurological phenotype in mulibrey nanism [51]. This evidence concerns the gene GDAP1 and mulibrey nanism.