Th3 cells were not more abundant in HSP patients, but activated Th3 cells (i.e., Th3 FoxP3 + cells) tended to be more abundant in the acute and remittent phases than in HCs (78.43% [50.62; 80.84] vs. 43.30% [40.20; 49.32], p = 0.135) (Fig. 1F). The gene discussed is FOXP3; the disease is hereditary spastic paraplegia.