UBXN10-AS1 acts as a tumour suppressor, regulating the miR-515-5p/SLIT3 axis, and the overexpression of UBXN10-AS1 could inhibit the proliferation of COAD cells in vitro and in vivo, working as an antitumour role. The gene discussed is UBXN10; the disease is colon adenocarcinoma.