To compile the literature evidence, English-language PubMed articles published before November 2022 were gathered using keywords ((“UBXD” OR “UBXN6” OR “UBXN4” OR “UBXN10” OR “UBXN2A” OR “UBXN11” OR “UBXN8” OR “UBXN7” OR “FAF2” OR “ASPSCR1” OR “NSFL1C” OR “UBXN2B” OR “FAF1” OR “UBXN1”) AND (“Cancer” OR “Tumour”)). Here, FAF1 is linked to neoplasm.