To compile the literature evidence, English-language PubMed articles published before November 2022 were gathered using keywords ((“UBXD” OR “UBXN6” OR “UBXN4” OR “UBXN10” OR “UBXN2A” OR “UBXN11” OR “UBXN8” OR “UBXN7” OR “FAF2” OR “ASPSCR1” OR “NSFL1C” OR “UBXN2B” OR “FAF1” OR “UBXN1”) AND (“Cancer” OR “Tumour”)). The gene discussed is UBXN4; the disease is neoplasm.