Patients in the VHL-CNS-Hb cohort had 18.7 inpatient admissions (including 175.2 inpatient days), 64.3 outpatient visits, 4.8 ED visits, and 7.2 other visits related to VHL-CNS-Hb per 100 person-years, resulting in mean annual medical costs of $22,379 (Tables 2 and 3). The gene discussed is GSTM1; the disease is von Hippel-Lindau disease.