VHL-associated CNS-Hb (VHL-CNS-Hb) is generally slow-growing and multifocal, with symptoms varying depending on location of the tumor (e.g., gait ataxia for cerebellar CNS-Hb and hypesthesia for spinal CNS-Hb) [2, 8]. Here, GSTM1 is linked to von Hippel-Lindau disease.