At the histopathological level, AD is a neurodegenerative disorder characterized by the cerebral accumulation of two distinctive lesions with extracellular deposits of β-amyloid peptides (Aβ) forming senile plaques and inclusions of abnormally phosphorylated Tau protein filaments primarily located within neurons leading to the formation of neurofibrillary tangles (NFTs) [4–6]. This evidence concerns the gene MAPT and Alzheimer disease.