ACE and schizophrenia: In the US and South Korea, the comparison between the ACE inhibitor and ARB groups for the risk of schizophrenia occurrence was not significant (US: IR 0.43/1 000 PY, 0.37/1 000 PY, calibrated HR 1.14 [95% CI, 0.98–1.32]; Korea: IR 0.44/1 000 PY, 0.22/1 000 PY, HR 1.47 [95% CI, 0.70–3.10]) (Fig. 3and Table 2).