IL6 is a pivotal proinflammatory cytokine in the nervous system.[39] Microdialysis studies have demonstrated significantly higher concentrations of IL6 in the perihematomal area compared to nonhematoma brain tissue within 20 to 26 hours following hematoma aspiration.[43] The human GSE24265 dataset further supports this, revealing significantly higher DEGs of IL6 around the hematoma compared to control tissue (LogFC = 2.390 and P value = 0.014; Table S5, Supplemental Digital Content, http://links.lww.com/MD/L375). The gene discussed is IL6; the disease is hematoma.