TNF and obstructive sleep apnea syndrome: It was proposed that MPV can serve as an alternative indicator to evaluate inflammation in individuals with OSAHS, quantifying its relationship with AHI, which helps determine the severity of OSAHS.There were proatherogenic molecules, including tumor necrosis factor-a (TNF-a), interleukin-6 (IL-6), oxidized low density lipoprotein cholesterol, correlated to increased resistance to insulin and active macrophages.