To begin to determine what might be the role of CCN1 expression by CAFs, we used CAF single-cell expression data to identify a group of six genes (PDGFRA, COL1A1, DCN, TAGLN, COL6A3, and LPAR1) that strongly correlated with CCN1 expression, yet were minimally expressed in other tumor cell types. This evidence concerns the gene COL6A3 and neoplasm.