The overexpression of Rac-1 has been associated to the development of cancers such as testicular cancer, head and neck squamous cell cancer, colorectal, pancreatic, and breast cancer, and leukemia (Ramos et al., 2022; An et al., 2023; Gupta et al., 2023; Nakhaei-Rad et al., 2023). Here, RAC1 is linked to cancer.