Finally, ELISA of both BALF and plasma indicated that DHA suppresses cSiO2-induced increases in IgG Abs reactive with cSiO2-killed macrophage (Mph) supernatant (Figure 11A), staurosporine-killed Mph supernatant (Figure 11B), and purified nucleosome (Figure 11C) in both BALF and plasma of lupus-prone NZBWF1 mice. The gene discussed is DDX41; the disease is systemic lupus erythematosus.