A chemokine-based “12-CK score” (CXCL9, CXCL10, CXCL11, CXCL13, CCL2, CCL3, CCL4, CCL5, CCL8, CCL18, CCL19 and CCL21) was initially proposed and developed based on colorectal cancer samples (146). Here, CCL21 is linked to colorectal cancer.