AFP and hepatocellular carcinoma: The AUROC curve and the best proposed cutoff value for HCC diagnosis were 88% with 12.35 ng/mL for AFP and 84.4% with 677.13 mAU/mL for PIVKA‐II, respectively, whereas the diagnostic accuracy for HCC diagnosis was slightly better (AUROC 90.2%) with the combination of the two biomarkers (Figure 1).