This finding was statistically significant for the OS when SFRP2 expression in tumour cells was considered (p = 0.022, Fig. 4c), but not for expression in the TME (p = 0.078, Fig. 4d) or when PFS was considered for SFRP2 expression in tumour cells (p = 0.061, Supplementary Fig. 5c) or TME (p = 0.566, Supplementary Fig. S5d). Here, SFRP2 is linked to neoplasm.